Research Opportunities

Local opportunities to participate in clinical research studies



University of Minnesota Memory-loss research projects seek participants

 
What 
Nationally known dementia researcher Dr. Joe Gaugler at the University of Minnesota is seeking subjects for several research studies. All studies are aimed at helping people with memory loss and their family caregivers.

Ongoing studies soliciting participants include:
  • An evaluation of remote health monitoring technology (eNeighbor) for persons with memory loss and family caregivers. If participants are randomly assigned to the eNeighbor group, they get to use the technology for free for 18 months (a value of over $4000). More Information
  • An evaluation of the Residential Care Transition Module, a 6-session, telephone-based support program for family members who have admitted a relative with memory loss to a nursing home, assisted living facility, or similar setting. More Information
  • An evaluation of a smartphone and watch that can assist in facial recognition for people with memory loss. More Information
When 
Variable, depending upon study 

Where 
Variable, depending upon study 

Contact 
Contact Joseph Gaugler at 612-626-2485 or gaug0015@umn.edu

HealthPartners Center for Memory and Aging research studies seek participants


Phase II Intranasal Insulin Study 
This investigation studies the effect of insulin on cognition and function in individuals with amnestic mild cognitive Impairment (aMCI) or mild Alzheimer’s disease (AD) when delivered as a nasal spray (intranasally).

Study Length
Eight months

For more information contact
HealthPartners Center for Memory & Aging
640 Jackson St. St. Paul, MN 55101
651-254-7000
memoryloss@healthpartners.com

HealthPartners Center for Memory and Aging research studies seek participants


Merck MK-831 017 Study 
This is a study in mild-moderate Alzheimer’s disease testing a novel drug (MK-8931) that is expected to reduce levels of Abeta, an abnormal protein that is associated with Alzheimer’s disease. This study sponsor is testing this agent to see if it has any effects in modifying the disease process. There is an option to participate in an extension study that will last up to 260 weeks
 
Study Length
78 weeks and an additional 260 weeks

For more information contact
HealthPartners Center for Memory & Aging
640 Jackson St. St. Paul, MN 55101
651-254-7000
memoryloss@healthpartners.com

HealthPartners Center for Memory and Aging research studies seek participants


Pilot Down Syndrome Study
This study investigates the effect of insulin on the memory and cognitive function in individuals with Down syndrome when delivered as a nasal spray (intranasally).

Study Length
Six weeks 

For more information contact
HealthPartners Center for Memory & Aging
640 Jackson St. St. Paul, MN 55101
651-254-7000
memoryloss@healthpartners.com

HealthPartners Center for Memory and Aging research studies seek participants


IDEAS Study 
This is a study to assess the impact of amyloid PET imaging on patient outcomes compared to standard of care alone. The results of this study will be used to help assess whether the Centers for Medicare and Medicaid Services (CMS) will cover the cost of this type of imaging in the future. This study does not use an intervention. 

Study Length
Three visits over approximately three months, CMS claims about your care may be used for up to three years

For more information contact
HealthPartners Center for Memory & Aging
640 Jackson St. St. Paul, MN 55101
651-254-7000
memoryloss@healthpartners.com

HealthPartners Center for Memory and Aging research studies seek participants


Dementia Confirmation
Currently, brain autopsy is the only way to definitively diagnose Alzheimer’s disease and associated dementias. Brain autopsies guide research into the causes and treatment of these disorders.

Contact
For more information about this study, please call 651-254-7000 and press 2 for Research.


International research study at Mayo Clinic seeks older individuals (ages 65-85) who have normal thinking and memory function as participants for the A4 Study


What
The A4 study invites older individuals (ages 65-85) who have normal thinking and memory function but who may be at risk for memory loss due to Alzheimer’s disease, but have no outward signs of the disease to participate in the study. Prospective participants will be screened to determine if they are appropriate participants for the study. For more information, please download the study flyer and brochure.

The purpose of the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s study (the "A4 study" for short) is to test whether a new investigational treatment, called an anti-amyloid antibody, can slow memory loss caused by Alzheimer’s disease.

The A4 study lasts for three years, and participants will be required to visit the clinical research site once a month.  Mayo Clinic is one of the sites for this international study.

When 
Three-year study with monthly participation  

Where
Mayo Clinic
Rochester, MN

Contact
Mayo Clinic
Attention: Sara Mason
507-284-1324 or a4study@mayo.edu
844-A4STUDY (247-8839) or brainlink@ucsd.org 

Ongoing clinical research studies



HealthPartners Center for Memory and Aging

 
Delirium Management
  • Delirium is a medical condition involving sudden changes in alertness.
  • Delirium complicates at least 20% of all hospital stays of patients 65 and older and can lead to further complications.
  • Studies show that cognitive decline accelerates in patients with dementia and delirium during hospitalization.
  • We are developing a hospital-wide program to reduce the incidence of delirium in older patients and ensure its early detection and enhanced treatment.
6th Vital Sign
We are administering a 3-minute cognitive screening test at clinical visits in subjects 70 or older without memory loss to test its feasibility and effectiveness in diagnosing Alzheimer’s disease earlier. If this disease can be diagnosed earlier, both dementia and comorbid chronic conditions may be treated more effectively.

For more information contact
HealthPartners Center for Memory & Aging
640 Jackson St. St. Paul, MN 55101
651-254-7000
memoryloss@healthpartners.com